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High Cholesterol May Trigger Breast Cancer Occurrence



For those who happen to have high cholesterol, you should be more careful. Because in addition could lead to complaints and some common diseases that have dketahui for this, high cholesterol levels were also able to trigger the onset of breast cancer.

This conclusion is expressed by the researchers after doing a research.
Research conducted by the experts was published in the journal Science.
In that study also describes how the problem of overweight or obesity could be the biggest risk factor in the onset of this disease.

So far, the problem of overweight or obesity is often associated with (as a trigger) of various types of cancer. Including colon cancer, uterine cancer breast dankanker.
This is due to the presence of fat deposits (excess) in people who have weight problems (obese) can pump various types of hormones, including estrogen, which is suspected to be the trigger for the growth of cancer.

In this research also examined on the use of drugs that lower cholesterol called statins.
The result, Statin drugs is considered to increase the expectations the use of drugs that lower cholesterol to prevent cancer.

Although cancer charity stated that it was too early to advise women to consume a low-cholesterol drugs, statins as prevention of breast cancer, but there is a study from Duke University Medical Center, in the United States showed that cholesterol has a similar effect.
According to experts, if the terms of the mechanism in the body, cholesterol is broken down into what is called 27HC, which can mimic the hormone estrogen and produce the same effect as a hormone in some tissues.

And of experiments have been conducted on mice, showed that the high-fat diet treatment, will improve 27HC levels in the blood, and may eventually lead to a 30% larger tumors than mice treated with normal diet.
This tumor is likely to spread.
And in human breast cancer tissue was able to grow more rapidly in laboratory tests when added with 27HC.

According to one expert researcher, Prof. Donald McDonnell said:
"Many studies have shown an association between obesity and breast cancer, and in particular high cholesterol is associated with breast cancer risk, but there is no mechanism that can be identified."
What we have found is the molecular us - not the cholesterol itself, but an excess of cholesterol metabolism - called 27HC that mimic the hormone estrogen and can lead to breast cancer. "

The above findings, the researchers stated that it would be raising hopes that by reducing cholesterol levels in the blood can reduce the risk of developing breast cancer.
Statin drugs has actually consumed by millions of people to reduce the risk of heart disease. And on the findings also indicate that the drug successfully Statins it can also be used to reduce the risk of breast cancer.

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