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MULTIPLE MYELOMA


CANCER DISEASES
CAUSE - DIAGNOSIS AND HEALING
( 31 TYPES OF CANCER IN HUMANS that you MUST KNOW )


MULTIPLE MYELOMA CANCER


Cases of multiple myeloma disease
Cases of multiple myeloma occupy 200/1000 , is regarded as the second most common malignancy of the blood . It occurs in older people , 50-65 years of age is a high incidence , age of onset in the last few years in advance . The incidence of males than females, the male to female ratio is 1.6:1 . With increasing age , the incidence of multiple myeloma will increase the life of the community and quality of life is an increasingly serious loss , parents should not be overlooked hematological malignancies . The incidence of multiple myeloma and race there is something slightly higher incidence rate of blacks .

What causes multiple myeloma
The cause of multiple myeloma can not be ascertained clearly , can be caused by ionizing radiation , severe antigenic stimulation , or EB virus associated with Kaposi's sarcoma herpes virus infection . Can also be associated with some cytokines , IL - 6 is a growth factor for multiple myeloma .

What are the symptoms of multiple myeloma
Symptoms in patients with multiple myeloma in addition to anemia is infection , bleeding , bone pain can occur ( most severe fractures ) , proteinuria ( uremia ) , other symptoms are blood hypercoagulability or venous thrombosis .
The rate of diagnosis of multiple myeloma at 40 % -50 % , the most common cause of diagnosis are :
1.Infeksi : patients are susceptible to respiratory infections and urinary tract infections , delay can cause death . Therefore , in elderly patients with persistent infection , should not be limited to anti-infective therapy , at the same time anti-infective therapy can search the main cause . If patients experience bone pain , anemia , bleeding and other symptoms should consider the possibility of this disease .
2.Anemia : in patients with multiple myeloma typically depressed bone marrow pressure can cause anemia .
3.Gejala on bone : bone pain , local mass , broken bones and even paralysis .
4.Hiperkalsemia : seen with symptoms such as vomiting , fatigue , confusion , polyuria , constipation , and other symptoms .
5.Hiperviskositas : usually seen with symptoms of dizziness , vertigo , tinnitus , can suddenly disturbed consciousness , numbness of the fingers , heart disorders , chronic heart failure and other symptoms .
6.Gangguan renal function : the time of diagnosis , patients often accompanied by renal insufficiency .

How to diagnose
Clinical findings , nearly two- thirds of patients in the early diagnosis and treatment when diagnosed with advanced , many patients due to the wrong part can be a misdiagnosis . Experts of 

Index of suspicion of multiple myeloma patients is quite high , imunoglobin must be timely , urine Bence Jones protein , X - ray radiography and bone marrow examination . X-ray examination with a lot of help diagnose the disease , can be found in a variety of sizes with a circular area some bone damage ( especially the bones of the skull , ribs , spine , pelvis ) , if necessary to a CT - scan or MRI . MRI exams can help find if there is compression of the bone marrow ; A CT scan can help show extramedullary lesion . Sometimes , only X-ray finding of multiple myeloma as a wide range of osteoporosis . Examination of multiple myeloma requires a multi - site examination of puncture or bone marrow biopsy .


ISS stage system
Phase standard ISS stage Average survival time ( months )
I In the blood β2 - MG < 3.5mg / L , albumin ≥ 35g / L 62
II Not according to the patient's stage I and III 45
III In the blood β2 - MG ≥ 5.5mg / L 29

Myeloma patients with stable without symptoms do not need treatment , just need to do regular visits to the hospital for examination ; meninggunya symptoms with blood , urine M protein or other clinical symptoms need treatment stiffened . Patients under the age of 70 years if possible try to do a stem cell transplant .

Several methods of treatment of myeloma
Integrative Medicine : Integrative Medicine is the treatment of choice . Patients during chemotherapy if it could be coupled with Chinese medicine to support the result of chemotherapy , reducing the side effects of chemotherapy to restore bone marrow function and boost the immune fungis . During chemotherapy will indigestion reaction , the drug will not be orally.
Chemotherapy : conventional therapy for the treatment of myeloma .
Radiotherapy : rarely used , is suitable for the treatment of focal myeloma , and with local bone pain symptoms until the pressure on the spinal cord .
Hematopoietic stem cell transplantation : allogeneic stem cell transplantation and autologous hematopoietic stem cell transplantation may be used for the treatment of multiple myeloma .

Several methods for home care
1 . The Rest : may perform usual activities , but should not perform strenuous activities , in order to avoid the fall or collision
2 . To avoid pathological fractures : make a bed with hard board , avoid using elastic mattress .
3 . Diets : give food high in calories, high in protein , rich in vitamins , foods that are easily digested . Patients with renal insufficiency , should be given a low -sodium diet , low in protein or wheat starch diet , to reduce the burden on the kidneys .
4 . For elderly patients with difficult-to- move should be assisted by gently flicking trackback body / light to avoid fractures . Give a massage with a warm towel on the skin , note the beds are always dry and flat to avoid decubitus .
5 . Oral treatment : patients with renal impairment , due to excessive accumulation of metabolites , some of the waste / garbage into the respiratory tract , causing bad breath , affects the patient's appetite , should do a good oral care , prevention of bacterial and fungal infections
6 . Psychological treatments : switch flavors patient concerns by providing love, attention , helping to ease the burden of mental patients , helping patients to face reality and get rid of the fear,
7 . Care and psychological : to make it easier for patients to express their concerns , to give love and attention to redouble their best to relieve the mental stress of patients , helping patients to face reality and get rid of the fear , help create the mood becomes stable.         


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